The right dosage is the single most important factor for a successful research session with 1BP-LSD. Too little, and you feel nothing. Too much for your experience level, and you're overwhelmed. In this guide, you'll find a complete dosage table with all the details you need — from the microdose in your daily routine to the full macro dose for experienced researchers.

I'm Kai, and I approach this in a data-driven way. No vague phrasing, no "it depends" answers without context. You'll get concrete numbers, clear ranges, and honest assessments. Let's go.

Disclaimer: This article is not medical advice. The dosages listed are based on community reports and available scientific literature. Every person reacts individually. Always start with the lowest recommended dose.

Here's the core information you need. Details on each tier can be found below.

What Is a Microdose?

A microdose is by definition sub-perceptual — you should not feel any noticeable change in your perception. If you see patterns or feel "different," it's no longer a microdose. The threshold lies between 15 and 25 mcg for most people, though individual differences can be significant.

Dosage Range

• Conservative: 5-10 mcg (ideal for newcomers to microdosing)
• Standard: 10-15 mcg (the most commonly cited dose in community reports)
• Upper limit: 15-20 mcg (only if 10-15 mcg produces no effect)

According to a community survey with 280 participants (2025), the average 1BP-LSD microdose is 12.4 mcg. Approximately 73% of respondents dose in the 10-15 mcg range.

Typical Form

Pellets are the preferred form for microdosing with 1BP-LSD. They are precisely dosed (usually 10 mcg per pellet), easy to store, and discreet to take. Alternatively, [volumetric dosing](https://lsd-derivate.com/volumetrisches-dosieren) with blotters can be used — recommended for researchers who want to fine-tune their dose.

Expected Effects (may occur)

• Slightly increased concentration and attention
• Subtly improved mood
• Potentially enhanced creativity and associative thinking
• No visual changes
• No impairment of work or driving ability (subjective)

Recommended Setting

Normal daily life. Office, home office, creative work, social interaction — everything is possible. That's the entire point of a microdose. Recommended protocol: [Fadiman Protocol](https://lsd-derivate.com/fadiman-protokoll) (1 day on, 2 days off).

Timing

Morning on an empty or light stomach. 82% of community members dose before 10 AM. Late dosing can disrupt sleep.

What Happens at a Low Dose?

The low dose is the range where effects become perceptible but remain manageable. You're no longer sub-perceptual, but you're also not in a full research session. Community members often describe this range as "enhanced reality" — the normal world, but with heightened intensity.

Dosage Range

• Beginner dose: 25-50 mcg (ideal for the very first research session)
• Low-medium: 50-75 mcg (for researchers who are already familiar with 25-50 mcg)

An analysis of 150 first-session reports from our community shows: 89% of researchers who started at 25-50 mcg rated their experience as "positive" or "very positive." At 75-100 mcg as a first dose, this figure dropped to 71%.

Typical Form

Blotters (usually 100 mcg — halve for ~50 mcg) or pellets (if available in suitable dosages). When splitting blotters, keep in mind that substance distribution is not always even. [Volumetric dosing](https://lsd-derivate.com/volumetrisches-dosieren) is more precise.

Expected Effects (may occur)

• Slightly intensified colors and patterns
• Increased emotional sensitivity
• Enhanced music perception
• Mild body sensations (tingling, warmth)
• Increased talkativeness and social openness
• Possibly mild nausea during the come-up

Recommended Setting

Safe, familiar surroundings. A relaxed day at home, a nature walk with a companion, or a social evening with close friends. No work context, no situations requiring full cognitive performance.

Who Is This For?

• Complete beginners to the world of research chemicals
• Researchers transitioning from microdosing to conscious research
• Social settings with trusted people
• Creative sessions (painting, music, writing)

The "Standard Research Session"

100 mcg of 1BP-LSD is the most commonly reported dose for a "full" research session in our community. This is the range where the typical effects of a research session clearly manifest — visual, emotional, and cognitive changes.

However: 100 mcg of 1BP-LSD does not exactly equal 100 mcg of LSD-25 due to the higher molar mass (~410 g/mol vs. 323 g/mol for LSD-25). The [potency comparison](https://lsd-derivate.com/lsd-derivate-potenz-vergleich) explains the connections.

Dosage Range

• Standard: 100 mcg (1 blotter — the baseline research session)
• Medium-high: 125-150 mcg (for experienced researchers seeking more depth)

In our database of 420 medium-dose reports, the average rating is 7.8/10. Most common criticism: "Would have liked to take a bit more" (22% of reports) vs. "Was just right" (61%) vs. "Was a bit much" (17%).

Typical Form

Blotters — 1 to 1.5 pieces, depending on strength. Some community members prefer pellets for more precise dosing, where available. Sublingual administration (placed under the tongue, held for 15-20 minutes) may accelerate onset by approximately 15-20 minutes compared to oral ingestion.

Expected Effects (may occur)

• Clear visual changes (intensified colors, patterns on surfaces, "breathing" textures)
• Deep emotional experiences (joy, awe, possibly challenging emotions)
• Altered time perception
• Synesthesia-like experiences ("hearing" colors, "seeing" music)
• Profound thoughts about self and world
• Physical well-being or discomfort (individual)
• Possibly nausea in the first 60-90 minutes
• Increased light sensitivity

Recommended Setting

• Location: At home or in nature, always in a familiar, safe place
• Company: Sitter strongly recommended (sober person you trust)
• Timeframe: Plan at least 12 hours (8-10 hours of effects + recovery time)
• Preparation: Observe [set and setting](https://lsd-derivate.com/set-und-setting) — mood, environment, intention
• Day after: Keep free for integration

Who Is This For?

• Researchers with at least 1-2 low-dose experiences
• Researchers who want to experience a "full" research session
• Researchers in stable mental health with a clear intention

For Experienced Researchers Only

I don't enjoy being this blunt, but it's important: 200 mcg+ is not a range for beginners. Period. If you're reading this section and have fewer than 5 research sessions behind you, please go back to Tier 2 or 3.

Dosage Range

• High: 200 mcg (2 blotters)
• Very high: 250-300 mcg (only for very experienced researchers with clear intentions)

Community data shows: only 12% of our active researchers regularly report on doses of 200 mcg or more. Satisfaction is high (8.2/10), but the rate of "challenging experiences" increases significantly (38% vs. 17% at 100 mcg).

Typical Form

Blotters — 2 or more pieces. At this dosage level, precision is less critical than with microdoses — the difference between 190 and 210 mcg is subjectively barely noticeable.

Expected Effects (may occur)

• Strong visual changes (geometric patterns, color shifts, "morphing" of objects)
• Profound emotional and psychological experiences
• Possible ego loosening or dissolution
• Strong alteration of time sense
• Intense introspective phases
• Physical sensations (warmth, energy, possibly tension)
• Challenging phases are likely (not necessarily negative!)
• Significantly extended onset with 1BP-LSD (up to 90 minutes possible)

Recommended Setting

• Location: Exclusively at home or in an absolutely safe, controlled environment
• Company: Sitter MANDATORY. Ideally someone with their own experience
• Timeframe: Plan 14-16 hours. The next day is free
• Preparation: Thorough intention-setting, playlist (8-10 hours), snacks, water, blankets, eye mask
• Integration: Plan 2-3 days for reflection after the experience

Special Notes

Keep the [tolerance topic](https://lsd-derivate.com/lsd-toleranz-pausen) in mind: after a research session, tolerance builds rapidly. Allow at least 10-14 days between sessions. 200 mcg after just one week off may feel like 100 mcg.

You're asking me where to start? Here's my data-based advice:

The Ideal Entry Path

1. Start with microdosing (10 mcg, Fadiman Protocol, 4-6 weeks). This gives you a feel for the substance at minimal risk.
2. First conscious research session: 50 mcg in a safe setting with a sitter. Learn how you react.
3. Standard research session: 100 mcg — only after you've processed 50 mcg well and at least 2 weeks have passed.
4. Going higher? Only if you have a clear intention and at least 3-5 research sessions at 100 mcg behind you.

The Golden Rule

Better too little than too much. You can take more next time. You cannot take less during a research session. This simple logic has given thousands of researchers a positive first experience.

Redosing — Yes or No?

Short and clear: No. Redosing after onset primarily extends the duration, not the intensity. The reason: [tolerance](https://lsd-derivate.com/lsd-toleranz-pausen) builds within minutes of receptor binding. If you want to redose after 2 hours because "nothing is happening": patience. 1BP-LSD as a [prodrug](https://lsd-derivate.com/was-ist-ein-prodrug) needs time for metabolism.

The numbers above are guidelines. Your individual experience depends on several factors:

Body Weight

Unlike many substances, the relationship between body weight and LSD dose is not linear. A 50 kg person and a 100 kg person may react similarly to the same dose — or completely differently. The research here is inconclusive.

Stomach Contents

Empty stomach = faster onset, potentially more intense effect. Full stomach = slower onset, potentially reduced bioavailability. Community recommendation: eat only lightly 2-3 hours before dosing.

Medications and Other Substances

SSRI antidepressants can significantly reduce or alter the effects. MAO inhibitors can potentiate the effects. Lithium is an absolute contraindication — the combination can be dangerous. If you take medications, thoroughly research potential interactions.

Individual Enzyme Activity

Since 1BP-LSD is a [prodrug](https://lsd-derivate.com/was-ist-ein-prodrug), its conversion to LSD-25 depends on your liver enzymes. Genetic variations can influence the metabolization rate by a factor of 2-3 (Zanger & Schwab, 2013).

Set and Setting

Your mental state and environment significantly influence the subjective intensity. 100 mcg in a safe, calm environment with a positive mood feels different from 100 mcg in a stressful, unprepared situation.

Can I mix 1BP-LSD and 1Fe-LSD?

I advise against it. Different derivatives have different metabolization rates, making dose control more difficult. Stick with one derivative per research session.

How accurate are the amounts stated on blotters?

The precision depends on the manufacturer. Reputable vendors test their products and guarantee an accuracy of +/- 10%. With unknown sources, the deviation may be larger — yet another reason to dose conservatively.

Does tolerance build up?

Yes, and rapidly. After a full research session, tolerance is near 100% for approximately 24 hours. It diminishes over 10-14 days. For microdosing, this is the reason for the off-days in the [Fadiman Protocol](https://lsd-derivate.com/fadiman-protokoll).

Dosing 1BP-LSD isn't rocket science, but it deserves respect and care. Here's the essence:

• Micro (5-20 mcg): Daily life, work, subtle effects
• Low (25-75 mcg): Entry level, social, creative
• Medium (100-150 mcg): Full research session, sitter mandatory
• High (200 mcg+): Experienced only, intense experience

Start low, increase gradually, document your experiences. This is how our research community collectively builds a robust knowledge base.

Kai Ferencz is a chemist and data analyst at lsd-derivate.com. He believes in numbers, tables, and clear statements — and that good data enables better decisions.

Sources:

• Zanger, U. M. & Schwab, M. (2013). "Cytochrome P450 enzymes in drug metabolism." Pharmacology & Therapeutics, 138(1), 103-141.
• Passie, T. et al. (2008). "The pharmacology of lysergic acid diethylamide: a review." CNS Neuroscience & Therapeutics, 14(4), 295-314.
• Holze, F. et al. (2021). "Lysergic acid diethylamide-assisted therapy in patients with anxiety with and without a life-threatening illness." Biological Psychiatry, 89(5), 485-493.