175mcg LSD Blotters

175mcg LSD blotters — higher research dose

You are looking for the 175mcg LSD blotter for advanced effect-profile studies? Reasonable. The 175 µg unit is an established higher research dose, sitting above the classic standard size and making deeper profile phases visible. Our batches are HPLC-tested, you pull the certificate of analysis via the batch number. Purity 99 %+, EU shipping in 48 hours, free from 50 €.

This page is a sub-category of All Blotters. Format-specific topics like absorbency, travel suitability and general storage are covered in detail there — here we focus on what sets the 175 µg dose apart from other doses.

What changes at the higher dose?

Compared to the 100 µg standard dose, the effect profile at 175 µg sits in a higher range — and not linearly. The plateau phase lengthens, Cmax climbs disproportionately to the acyl hydrolysis, and total duration shifts upwards. For research groups looking to measure profile depth and sub-acute effect phases, 175 µg is the next established step up.

Available compounds

Our 175 µg blotters come with two compounds: the compound 1Bp-LSD and the compound 1Fe-LSD. Both are 1-acylated lysergamides, both are hydrolytically converted to LSD-25 via their respective acyl group — at a higher dose, accordingly, with a higher end quantity in plasma. Which compound fits your research design depends on which hydrolysis profile and which onset are in focus.

What is behind the 175 µg variant?

A 175 µg blotter is a perforated paper square — typically 7.5 × 7.5 mm to 10 × 10 mm — impregnated with exactly 175 micrograms of a 1-acylated lysergamide. The compound quantity results from controlled volumetric dosing with a higher concentration of carrier solution than in the standard variant. With clean production, variation per square stays below ±5 %.

175 µg as a higher dose in research design

The 175 µg unit has established itself in recent lysergamide literature as an intermediate dose between the classic standard size (100 µg) and the peak dose (200 µg). It delivers enough signal for deep profile phases but stays below the range in which non-linear saturation effects at the 5-HT2A receptor dominate. Standard duration in this dose range falls between 10 and 14 hours, with oral onset at 30–60 minutes.

Suitability for advanced studies

Anyone who has established the standard profile at 100 µg and wants to investigate high-dose effects typically moves next to the 175 µg dose. Here sub-acute profile phases become visible that would otherwise vanish into noise at lower doses — for example late plateau effects, long tailing phases and individual variability in acyl hydrolysis. Anyone who wants to drop back to the 100 µg variant will find it as the 100 mcg variant.

Profile depth and duration phase

Compared to the 100 µg dose, the plateau phase at 175 µg lengthens by an average of 2–3 hours. That is not "more effect" but a different effect-phase structure — relevant for studies where duration characteristics are the central variable. For bioavailability series with a high signal-to-noise ratio, the 175 µg dose delivers more robust data points than the 100 µg variant.

Compound choice: 1Bp-LSD vs. 1Fe-LSD at higher dose

Both variants hydrolyse to LSD-25 in vivo, but via different acyl groups — 1Bp-LSD via the butanoyl/bromobenzoyl group, 1Fe-LSD via the furoyl group. At higher doses, the influence of acyl chain structure on the hydrolysis profile becomes more clearly visible than at lower doses. Anyone wanting to isolate substituent-specific PK effects gains data points with a better signal-to-noise ratio at the 175 µg dose.

Quality assurance and laboratory analysis

At higher doses, dose stability across the study period is particularly relevant. Each batch is analysed by HPLC; purity, identity and compound quantity per sheet are checked. Anything below 99 % purity does not go on sale.

HPLC quantification of the 175 µg unit

After impregnation, individual 175 µg blotters are extracted from the sheet on a sample basis and the compound content is verified. Tolerance per square: below ±5 %. At higher doses, the absolute variation in micrograms is larger, but the percentage is identical to the standard variant. For reproducible study series, the constant tolerance limit is decisive.

GC-MS identity confirmation

On selected batches GC-MS is applied to confirm molecular identity through mass spectrometry. Important, because 1-acylated lysergamides can have chromatographically similar retention times — mass spectrometry delivers the unambiguous proof that the declared derivative is actually present in the batch.

Stability and storage

With correct storage (dry, dark, 2–8 °C, light-tight packaging) 175 µg blotters stay stable for at least 12 months. The higher absolute compound quantity in the blotter does not change basic stability — lysergamides react proportionally to light and oxygen, not depending on absolute concentration. Keep the original packaging sealed.

175mcg vs. 100mcg vs. 200mcg — doses compared

Applications of the 175 µg variant in research

The 175 µg dose lands above all where the standard profile at 100 µg is already captured and deeper or longer effect phases are to be investigated. In practice this covers several research areas.

Advanced effect-profile studies

Anyone characterising plateau phase, late tailing effects and individual duration variability needs a dose with a high signal-to-noise ratio. At 175 µg the plateau and tailing phases are measurably extended (10–14 h vs. 8–12 h at 100 µg), which yields statistically more robust datasets.

Acyl-substituent comparison studies

The influence of the acyl group on hydrolysis rate and bioavailability becomes more clearly visible at higher doses. Anyone setting 1Bp-LSD against 1Fe-LSD gains data points with better resolution of substituent-specific PK profiles through 175 µg comparison studies. Both compounds in parallel from the same study series — that eliminates batch-specific variability.

Sub-acute effect phases and tailing

The late phases of a lysergamide profile — anything after Tmax+6 h — often sit below the measurement limit at lower doses for mood and cognitive endpoints. At 175 µg these phases stay above the detection threshold long enough that tailing characteristics and individual variability can be captured.

Bioavailability studies with high signal

For absolute and relative bioavailability determinations, higher doses are often more practical — plasma signal is clearer, analytical tolerance limits relatively lower. With 175 µg blotters, AUC, Cmax and Tmax can be determined at a better signal-to-noise ratio than with 100 µg units.

Ordering 175 µg blotters — simple and discreet

You want to order 175 µg blotters? Three steps: choose compound (1Bp-LSD or 1Fe-LSD), pick quantity, complete the order. Shipped in discreet neutral packaging.

Fast ordering process

Orders placed by 14:00 ship the same working day. For comparison studies between 1Bp-LSD and 1Fe-LSD we recommend parallel ordering of both compounds from batches with similar production dates — that reduces batch-specific variability as a confounder.

Flexible payment options

Accepted: bank transfer (SEPA), cryptocurrencies and other secure payment routes. Encrypted transmission is standard.

Discreet EU shipping in 48 hours

Neutral packaging, no indication of contents or sender. EU delivery time 24–48 hours, free from 50 € order value. Tracking arrives by email.

Frequent questions on the 175 µg variant